RTN3 antibody [1E11]

GeneTex

RTN3 antibody [1E11]

9

ICC/IF: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

Unconjugated

RTN3

reticulon 3

ASYIP, HAP, NSPL2, NSPLII, RTN3-A1, reticulon-3, ASY interacting protein, NSP-like protein 2, NSP-like protein II, homolog of ASY protein, neuroendocrine-specific protein-like 2, neuroendocrine-specific protein-like II

Mouse

IgG2a

Reticulon-3

This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]

-20°C or -80°C,2°C to 8°C

12352203