RU-SKI 43 [1043797-53-0]
HY-18366
CAS Number1043797-53-0
Product group Chemicals
Molecular Weight386.55
Overview
- SupplierMedChem Express
- Product NameRU-SKI 43 [1043797-53-0]
- Delivery Days Customer10
- CAS Number1043797-53-0
- CertificationResearch Use Only
- Molecular FormulaC22H30N2O2S
- Molecular Weight386.55
- Scientific DescriptionRU-SKI 43 is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. RU-SKI 43 reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 has anti-cancer activity[1].
- SMILESO=C(CNCC(C)CC)N1CCC2=C(C=CS2)C1COC3=CC=CC(C)=C3
- UNSPSC12352200