RU-SKI 43 [1043797-53-0]
T12797
CAS Number1043797-53-0
Product group Chemicals
Estimated Purity99.78%
Molecular Weight386.55
Overview
- SupplierTargetMol Chemicals
- Product NameRU-SKI 43 [1043797-53-0]
- Delivery Days Customer9
- CAS Number1043797-53-0
- CertificationResearch Use Only
- Chemical NameRU-SKI 43
- Estimated Purity99.78%
- Molecular FormulaC22H30N2O2S
- Molecular Weight386.55
- Scientific DescriptionRU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.
- Shelf life instruction3 years
- SMILESC(OC1=CC(C)=CC=C1)C2C3=C(CCN2C(CNCC(CC)C)=O)SC=C3
- Storage Instruction-20°C
- UNSPSC12352200
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