Ruboxistaurin hydrochloride [169939-93-9]

TargetMol Chemicals

Ruboxistaurin hydrochloride

9

169939-93-9

Chemical

Research Use Only

Ruboxistaurin hydrochloride

98.44%

C28H28N4O3 HCl

505.01

Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCbetaI and PKCbetaII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCbeta over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 microM for PKCeta, -delta, -gamma, -alpha, -epsilon and -aeta respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).

3 years

Cl.CN(C)CC1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21

-20°C

12352200