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RUNX1 antibody

GTX129100
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRUNX1
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Overview

  • Supplier
    GeneTex
  • Product Name
    RUNX1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.15 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID861
  • Target name
    RUNX1
  • Target description
    RUNX family transcription factor 1
  • Target synonyms
    acute myeloid leukemia 1 protein; AML1; AML1-ETO fusion; AML1-ETO fusion protein; AML1-EVI-1; AML1-EVI-1 fusion protein; AMLCR1; CBF2alpha; CBFA2; core-binding factor, runt domain, alpha subunit 2; EVI-1; mutant RUNX1; oncogene AML-1; PEA2-alpha B; PEBP2aB; PEBP2alpha; PEBP2-alpha B; polyomavirus enhancer-binding protein 2 alpha B subunit; runt related transcription factor 1; runt-related transcription factor 1; SL3/AKV core-binding factor alpha B subunit; SL3-3 enhancer factor 1 alpha B subunit
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ01196
  • Protein Name
    Runt-related transcription factor 1
  • Scientific Description
    Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Atypical GATA protein TRPS1 plays indispensable roles in mouse two-cell embryo. Liu Y et al., 2019 Feb, Cell Cycle
    Read more
  • Runt-related transcription factor 1 (RUNX1) deficiency attenuates inflammation-induced pro-inflammatory and pro-labour mediators in myometrium. Lappas M, 2018 Sep 15, Mol Cell Endocrinol
    Read more