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SA1 antibody

Name: SA1 antibody
SKU: GTX129912_G10
Availability: BackOrder

GTX129912

ApplicationsImmunoPrecipitation, Western Blot

Product group Antibodies

ReactivityHuman

TargetSTAG1

Overview

Supplier
GeneTex
Product Name
SA1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoPrecipitation, Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.53 mg/ml
Conjugate
Unconjugated
Gene ID10274
Target name
STAG1
Target description
STAG1 cohesin complex component
Target synonyms
MRD47, SA1, SCC3A, cohesin subunit SA-1, SCC3 homolog 1, nuclear protein stromal antigen 1, sister chromatid cohesion 3 homolog A, stromal antigen 1
Host
Rabbit
Isotype
IgG
Protein IDQ8WVM7
Protein Name
Cohesin subunit SA-1
Scientific Description
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008]
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Hoffmann T, Hörmann A, Corcokovic M, et al. Precision RNAi using synthetic shRNAmir target sites. Elife. 2023,12. doi: 10.7554/eLife.84792
Read this paper
Bailey ML, Tieu D, Habsid A, et al. Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene STAG2. Life Sci Alliance. 2021,4(11). doi: 10.26508/lsa.202101083
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van der Lelij P, Newman JA, Lieb S, et al. STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers. Life Sci Alliance. 2020,3(7). doi: 10.26508/lsa.202000725
Read this paper
van der Lelij P, Lieb S, Jude J, et al. Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts. Elife. 2017,6:pii: e26980. doi: 10.7554/eLife.26980.
Read this paper