WB analysis of various sample lysates using GTX66596 Salvador homolog 1 antibody. Dilution : 1:1000 Loading : 25microg per lane
Salvador homolog 1 antibody
GTX66596
Overview
- SupplierGeneTex
- Product NameSalvador homolog 1 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID60485
- Target nameSAV1
- Target descriptionsalvador family WW domain containing protein 1
- Target synonyms1700040G09Rik; 45 kDa WW domain protein; hWW45; protein salvador homolog 1; salvador homolog 1; SAV; WW domain-containing adaptor 45; WW45; WWP4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionWW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203