Samuraciclib

AbMole BioScience

Samuraciclib

9

1805833-75-3

Chemical

Research Use Only

C22H30N6O

394.51

Samuraciclib (CT7001) is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. Samuraciclib inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 uM. Samuraciclib has anti-tumor effects.

Please store the product under the recommended conditions in the Certificate of Analysis.

12352200