SAR-439859
ORB1089364
CAS Number2114339-57-8
Product group Chemicals
Molecular Weight554.4792104
Overview
- SupplierBiorbyt
- Product NameSAR-439859 [2114339-57-8]
- Delivery Days Customer10
- CAS Number2114339-57-8
- CertificationResearch Use Only
- Molecular FormulaC31H30CL2FNO3
- Molecular Weight554.4792104
- Scientific DescriptionSAR439859 is an orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SAR439859 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells
- SMILESClC1C=C(C=CC=1C1CCCC2C=C(C(=O)O)C=CC=2C=1C1C=CC(=CC=1)O[C@H]1CCN(CCCF)C1)Cl
- UNSPSC12352200
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