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ProductsBack/SB 203580 hydrochloride

SB 203580 hydrochloride

ORB1909166

CAS Number869185-85-3

Product group Chemicals

Estimated Purity98.00%

Molecular Weight413.9

Overview

Supplier
Biorbyt
Product Name
SB 203580 hydrochloride
Delivery Days Customer
10
CAS Number
869185-85-3
Certification
Research Use Only
Estimated Purity
98.00%
Molecular Formula
C21H17ClFN3OS
Molecular Weight
413.9
Scientific Description
SB 203580 hydrochloride (Adezmapimod hydrochloride) is a selective, ATP-competitive p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy and inhibits SAPK2a/p38, SAPK2b/p38beta2, LCK, GSK3beta, and PKBalpha. SB 203580 hydrochloride has been shown to be useful in antiretroviral therapy. 203580 hydrochloride inhibits amphoteric mechanical anomalous pain in a mouse model of antiretroviral-induced neuropathic pain.
SMILES
Cl.O=S(C=1C=CC(=CC1)C2=NC(C=3C=CN=CC3)=C(N2)C=4C=CC(F)=CC4)C
Storage Instruction
-20°C
UNSPSC
12352200

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