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SB 203580 hydrochloride [869185-85-3]
T21675
Overview
- SupplierTargetMol Chemicals
- Product NameSB 203580 hydrochloride [869185-85-3]
- Delivery Days Customer14
- CAS Number869185-85-3
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameSB 203580 hydrochloride
- Molecular FormulaC21H17ClFN3OS
- Molecular Weight413.9
- Scientific DescriptionAdezmapimod (SB 203580) hydrochloride is a selective ATP-competitive inhibitor of p38 MAPK, with IC50 values of 50 nM for SAPK2a/p38 and 500 nM for SAPK2b/p38beta2. This compound also inhibits LCK, GSK3beta, and PKBalpha with IC50 values 100-500 times higher than those for SAPK2a/p38. Additionally, Adezmapimod hydrochloride acts as an activator of autophagy and mitophagy [1].
- Shelf life instruction3 years
- SMILESCl.CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1
- Storage Instruction-20°C
- UNSPSC12352200