SB-277011 (dihydrochloride) [1226917-67-4]

MedChem Express

SB-277011 (dihydrochloride) [1226917-67-4]

10

1226917-67-4

Research Use Only

C28H32Cl2N4O

511.49

SB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, 3, D2, 5-HT1B, and 5-HT1D receptors, respectively.

O=C(C1=CC=NC2=CC=CC=C12)N[C@H]3CC[C@H](CCN4CC5=C(C=C(C#N)C=C5)CC4)CC3.[H]Cl.[H]Cl

12352200