SB-277011 (hydrochloride) [215804-67-4]
HY-10847B
CAS Number215804-67-4
Product group Chemicals
Estimated Purity99.59
Molecular Weight475.02
Overview
- SupplierMedChem Express
- Product NameSB-277011 (hydrochloride) [215804-67-4]
- Delivery Days Customer9
- CAS Number215804-67-4
- CertificationResearch Use Only
- Estimated Purity99.59
- Molecular FormulaC28H31ClN4O
- Molecular Weight475.02
- Scientific DescriptionSB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor (D3R) antagonist with Ki values of 10.7 nM and 11.2 nM at rodent and human D3R, respectively. SB-277011 hydrochloride displays 80- to 100-fold selectivity over other dopamine receptors with pKis of 8.0, 6.0, 1B, and 5-HT1D receptors, respectively[1][2].
- SMILESO=C(C1=CC=NC2=CC=CC=C21)N[C@@H]3CC[C@H](CC3)CCN4CC5=C(CC4)C=C(C#N)C=C5.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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![SB-277011 hydrochloride [215804-67-4]](https://www.targetmol.com/group3/M00/37/90/CgoaEWayTsCEWomvAAAAAM1ts4Q306.png)
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