SB-277011 hydrochloride [215804-67-4]
T63096
CAS Number215804-67-4
Product group Chemicals
Estimated Purity98.54%
Molecular Weight475.03
Overview
- SupplierTargetMol Chemicals
- Product NameSB-277011 hydrochloride [215804-67-4]
- Delivery Days Customer14
- CAS Number215804-67-4
- CertificationResearch Use Only
- Chemical NameSB-277011 hydrochloride
- Estimated Purity98.54%
- Molecular FormulaC28H31ClN4O
- Molecular Weight475.03
- Scientific DescriptionSB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, and orally active dopamine D3 receptor (D3R) antagonist that crosses the blood-brain barrier, with Ki values of 10.7 nM for rodent D3R and 11.2 nM for human D3R. It is 80-100 times more selective for D3 receptors than other dopamine receptors, acting on D3 receptors (pKi: 8.0), D2 receptors (pKi: 6.0), 5-HT1B receptors (pKi < 5.2), and 5-HT1D receptors (pKi: 5.9).
- Shelf life instruction3 years
- SMILESC(N[C@@H]1CC[C@@H](CCN2CC=3C(CC2)=CC(C#N)=CC3)CC1)(=O)C=4C5=C(N=CC4)C=CC=C5.Cl
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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