SB-657510 [474960-44-6]
T12848
CAS Number474960-44-6
Product group Chemicals
Estimated Purity98.03%
Molecular Weight505.81
Overview
- SupplierTargetMol Chemicals
- Product NameSB-657510 [474960-44-6]
- Delivery Days Customer4
- CAS Number474960-44-6
- CertificationResearch Use Only
- Chemical NameSB-657510
- Estimated Purity98.03%
- Molecular FormulaC19H22BrClN2O5S
- Molecular Weight505.81
- Scientific DescriptionSB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting UII-induced inflammatory mediators, such as adhesion molecules, in human vascular endothelial cells and upregulation of cytokines and tissue factors. SB 657510 has a therapeutic effect on diabetes-related atherosclerotic disease in diabetic mouse models.
- Shelf life instruction3 years
- SMILESCOc1cc(Br)c(cc1OC)S(=O)(=O)Nc1ccc(Cl)c(O[C@@H]2CCN(C)C2)c1
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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