
WB analysis of Jurkat lysate using GTX89599 SCAP2 antibody, C-term. Dilution : 0.5microg/ml Loading : 35microg protein in RIPA buffer
SCAP2 antibody, C-term
GTX89599
Overview
- SupplierGeneTex
- Product NameSCAP2 antibody, C-term
- Delivery Days Customer7
- Application Supplier NoteWB: 0.5-2microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID8935
- Target nameSKAP2
- Target descriptionsrc kinase associated phosphoprotein 2
- Target synonymsFyn-associated phosphoprotein SKAP55 homologue; PRAP; Pyk2/RAFTK-associated protein; RA70; retinoic acid-induced protein 70; SAPS; SCAP2; SKAP55 homolog; SKAP-55HOM; SKAP55R; SKAP-HOM; src family-associated phosphoprotein 2; src kinase-associated phosphoprotein 2; src kinase-associated phosphoprotein of 55-related protein; src-associated adapter protein with PH and SH3 domains
- HostGoat
- IsotypeIgG
- Protein IDO75563
- Protein NameSrc kinase-associated phosphoprotein 2
- Scientific DescriptionThe protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203