
WB analysis of human liver tissue lysate using GTX85270 SCARA5 antibody. Working concentration : 1 microg/ml
SCARA5 antibody
GTX85270
Overview
- SupplierGeneTex
- Product NameSCARA5 antibody
- Delivery Days Customer9
- Antibody SpecificityAt least four isoforms of SCARA5 are known to exist; this antibody will detect all four isoforms.
- Application Supplier NoteWB: 1 microg/mL. ICC/IF: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID286133
- Target nameSCARA5
- Target descriptionscavenger receptor class A member 5
- Target synonymsNET33; scavenger receptor class A member 5; scavenger receptor class A, member 5 (putative); scavenger receptor hlg; Tesr; testis expressed scavenger receptor
- Protein IDQ6ZMJ2
- Protein NameScavenger receptor class A member 5
- Scientific DescriptionScavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains that collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery. At least four isoforms of SCARB1 are known to exist.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- TGF-beta1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB. Huang SC et al., 2017 Dec, EMBO Mol MedRead more