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SDHA antibody

GTX101689
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSDHA
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Overview

  • Supplier
    GeneTex
  • Product Name
    SDHA antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.31 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6389
  • Target name
    SDHA
  • Target description
    succinate dehydrogenase complex flavoprotein subunit A
  • Target synonyms
    CMD1GG, FP, MC2DN1, NDAXOA, PGL5, PPGL5, SDH1, SDH2, SDHF, succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, flavoprotein subunit of complex II, malate dehydrogenase [quinone] flavoprotein subunit, succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP31040
  • Protein Name
    Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • Scientific Description
    This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Toda T, Ito M, Takeda JI, et al. Extremely low-frequency pulses of faint magnetic field induce mitophagy to rejuvenate mitochondria. Commun Biol. 2022,5(1):453. doi: 10.1038/s42003-022-03389-7
    Read this paper
  • Imai Y, Inoshita T, Meng H, et al. Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson's disease. Commun Biol. 2019,2:424. doi: 10.1038/s42003-019-0674-1
    Read this paper
  • Sánchez I, Balagué E, Matilla-Dueñas A. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1). Hum Mol Genet. 2016,25(18):4021-4040. doi: 10.1093/hmg/ddw242
    Read this paper