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T74600 | Keap1-Nrf2-IN-9 | All TargetMol Chemicals products available at Bio-Connect

Keap1-Nrf2-IN-9 | T74600 | TargetMol Chemicals

Keap1-Nrf2-IN-9 [2769963-24-6]

We offer a wide range of chemicals that includes biochemicals, click chemistry products, inhibitors, small molecules, amino acid derivatives, antibiotics, (blocking) buffers, adjuvant, solvents and diluents as well as stains, labels and dyes.<br><br>You will find many categories within the assay product group, so you can select one to find the product you need quickly. Click on one of the categories for an overview of our products.

Bio-Connect offers a wide range of chemicals that includes biochemicals, click chemistry products, inhibitors, small molecules and many more.

Bio-Connect supplier for all your research chemicals

Keap1-Nrf2-IN-9 (compound 11) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with an IC50 value of 0.575 microM, enhancing the expression of Nrf2 target genes such as heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits, while not being cytotoxic to ARPE19 cells [1].

HY-147517 | Keap1-Nrf2-IN-9 | MW: 670.71 | Formula: C31H30N2O11S2 | MedChem Express is available at Bio-Connect

Keap1-Nrf2-IN-9 | HY-147517 | MedChem Express

Keap1-Nrf2-IN-9

Keap1-Nrf2-IN-9 (compound 11) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein-protein interaction) inhibitor with an IC50 of 0.575 microM. Keap1-Nrf2-IN-9 increases the expression of Nrf2 target genes including heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits. Keap1-Nrf2-IN-9 shows not cytotoxic activity in ARPE19 cells[1].

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