
WB analysis of various sample lysates using GTX32863 Seladin 1 antibody. Dilution : 1:1000 Loading : 25microg per lane
Seladin 1 antibody
GTX32863
Overview
- SupplierGeneTex
- Product NameSeladin 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1718
- Target nameDHCR24
- Target description24-dehydrocholesterol reductase
- Target synonyms3 beta-hydroxysterol delta 24-reductase; DCE; delta(24)-sterol reductase; desmosterol-to-cholesterol enzyme; diminuto/dwarf1 homolog; Nbla03646; seladin 1; SELADIN1; seladin-1; selective AD indicator 1
- HostRabbit
- IsotypeIgG
- Protein IDQ15392
- Protein NameDelta(24)-sterol reductase
- Scientific DescriptionThis gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203