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Seladin 1 antibody [HL3253]

GTX640900
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDHCR24
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Overview

  • Supplier
    GeneTex
  • Product Name
    Seladin 1 antibody [HL3253]
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody was raised against human Seladin 1 Intracellular domain.
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HL3253
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1718
  • Target name
    DHCR24
  • Target description
    24-dehydrocholesterol reductase
  • Target synonyms
    3 beta-hydroxysterol delta 24-reductase; DCE; delta(24)-sterol reductase; desmosterol-to-cholesterol enzyme; diminuto/dwarf1 homolog; Nbla03646; seladin 1; SELADIN1; seladin-1; selective AD indicator 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15392
  • Protein Name
    Delta(24)-sterol reductase
  • Scientific Description
    This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203