Seladin 1 antibody [HL3253]

GeneTex

Seladin 1 antibody [HL3253]

7

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

HL3253

1 mg/ml

Unconjugated

DHCR24

24-dehydrocholesterol reductase

3 beta-hydroxysterol delta 24-reductase; DCE; delta(24)-sterol reductase; desmosterol-to-cholesterol enzyme; diminuto/dwarf1 homolog; Nbla03646; seladin 1; SELADIN1; seladin-1; selective AD indicator 1

Rabbit

IgG

Delta(24)-sterol reductase

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203