Senicapoc

MedChem Express

Senicapoc [289656-45-7]

5

289656-45-7

Research Use Only

99.88

C20H15F2NO

323.34

Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca 2+ -activated K + channel; KCa3.1 ) blocker with an IC 50 of 11 nM. Senicapoc blocks Ca 2+ -induced rubidium flux from human RBCs with an IC 50 value of 11 nM and inhibits RBC dehydration with IC 50 of 30 nM [1] .

O=C(C(C1=CC=CC=C1)(C2=CC=C(C=C2)F)C3=CC=C(F)C=C3)N

-20°C,2°C to 8°C

12352200