
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA028785(SETD2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
SETD2 Antibody
CSB-PA028785
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetSETD2
Overview
- SupplierCusabio
- Product NameSETD2 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID29072
- Target nameSETD2
- Target descriptionSET domain containing 2, histone lysine methyltransferase
- Target synonymsHBP231; HIF-1; HIP-1; histone-lysine N-methyltransferase SETD2; HSPC069; huntingtin interacting protein 1; huntingtin yeast partner B; huntingtin-interacting protein B; HYPB; KMT3A; LLS; lysine N-methyltransferase 3A; p231HBP; protein-lysine N-methyltransferase SETD2; SET2
- HostRabbit
- IsotypeIgG
- Protein IDQ9BYW2
- Protein NameHistone-lysine N-methyltransferase SETD2
- Scientific DescriptionHuntingtons disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203