SETD7 Antibody

Cusabio

SETD7 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

SETD7

SET domain containing 7, histone lysine methyltransferase

KMT7, SET7, SET7/9, SET9, histone-lysine N-methyltransferase SETD7, H3-K4-HMTase SETD7, SET domain containing 7, lysine methyltransferase, SET domain containing lysine methyltransferase 7, SET domain-containing protein 7, histone H3-K4 methyltransferase SETD7, histone H3-lysine 4-specific methyltransferase, lysine N-methyltransferase 7

Rabbit

IgG

Histone-lysine N-methyltransferase SETD7

The methylation of histones plays a pivotal role in the regulation of chromatin structure and gene expression. Histone methylation can occur on Arg or Lys residues, with an exquisite site selectivity for Lys methylation at specific positions in the N-termini of histones H3 and H4. SET7/9, a histone methyltransferase (HMTase), which transfers methyl groups to Lys4 of histone H3, forms a complex with S-adenosyl-L-methionine. This complex contains an active site consisting of a binding pocket where an AdoMet molecule in an unusual conformation binds, a narrow substrate-specific channel that only unmethylated lysine residues can access and a catalytic tyrosine residue.

Human, Mouse

-20°C or -80°C

41116161