SETDB1 antibody [N1], N-term
![Research Use Only](static/images/certificates/ruo.jpg)
GTX115305
ApplicationsImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSETDB1
Overview
- SupplierGeneTex
- Product NameSETDB1 antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.53 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID9869
- Target nameSETDB1
- Target descriptionSET domain bifurcated histone lysine methyltransferase 1
- Target synonymsERG-associated protein with a SET domain, ESET; ESET; H3-K9-HMTase4; histone H3-K9 methyltransferase 4; histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase, H3lysine-9 specific 4; KG1T; KMT1E; lysine N-methyltransferase 1E; SET domain bifurcated 1; TDRD21; tudor domain containing 21
- HostRabbit
- IsotypeIgG
- Protein IDQ15047
- Protein NameHistone-lysine N-methyltransferase SETDB1
- Scientific DescriptionThis gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States. Wu K et al., 2020 Jan 7, Cell RepRead more
- Significance of histone methyltransferase SETDB1 expression in colon adenocarcinoma. Ho YJ et al., 2017 Nov, APMISRead more
- H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Chen J et al., 2013 Jan, Nat GenetRead more