SH3RF1 Antibody, Biotin conjugated

Cusabio

SH3RF1 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

SH3RF1

SH3 domain containing ring finger 1

E3 ubiquitin-protein ligase SH3RF1; plenty of SH3 domains; plenty of SH3s; POSH; putative E3 ubiquitin-protein ligase SH3RF1; ring finger protein 142; RING-type E3 ubiquitin transferase SH3RF1; RNF142; SH3 domain-containing RING finger protein 1; SH3 multiple domains 2; SH3 multiple domains protein 2; SH3MD2

Rabbit

IgG

E3 ubiquitin-protein ligase SH3RF1

Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Human

-20°C or -80°C

12352203