SH3RF1 antibody

Biorbyt

SH3RF1 antibody

16

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SH3RF1.

Western Blot

WB:1:1000-1:3000 WB

Research Use Only

Polyclonal

100 ug/ml

Unconjugated

SH3RF1

SH3 domain containing ring finger 1

E3 ubiquitin-protein ligase SH3RF1; plenty of SH3 domains; plenty of SH3s; POSH; putative E3 ubiquitin-protein ligase SH3RF1; ring finger protein 142; RING-type E3 ubiquitin transferase SH3RF1; RNF142; SH3 domain-containing RING finger protein 1; SH3 multiple domains 2; SH3 multiple domains protein 2; SH3MD2

Rabbit

E3 ubiquitin-protein ligase SH3RF1

Rabbit polyclonal to SH3RF1. E3 ubiquitin-protein ligase SH3RF1 belongs to the SH3RF family. SH3RF1 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3RF1 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Human, Mouse

-20°C

12352203