Sheep anti Mouse LFC
X1089P
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityMouse
TargetARHGEF2
Overview
- SupplierNordic-MUbio
- Product NameSheep anti Mouse LFC
- Delivery Days Customer7
- Application Supplier NoteDetects Lfc in mouse tissues by immunoprecipitation-Western blot at 4 microg/ml. Detects a 118 kDa band in mouse tissue extracts corresponding to wild-type Lfc. Can also be used in immunofluorescence assays. Optimal concentration should be evaluated by serial dilutions.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot
- Applications SupplierWestern Blotting;Immunoprecipitation;Immunofluorescence;Western Blotting
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9181
- Target nameARHGEF2
- Target descriptionRho/Rac guanine nucleotide exchange factor 2
- Target synonymsGEF; GEFH1; GEF-H1; guanine nucleotide exchange factor H1; Lfc; LFP40; microtubule-regulated Rho-GEF; NEDMHM; P40; proliferating cell nucleolar antigen p40; rho guanine nucleotide exchange factor 2; Rho/Rac guanine nucleotide exchange factor (GEF) 2
- HostSheep
- IsotypeIgG
- Protein IDQ92974
- Protein NameRho guanine nucleotide exchange factor 2
- Scientific DescriptionRho guanine nucleotide exchange factor 2, ARHGEF2
- Shelf life instructionSee expiration date on vial
- ReactivityMouse
- Reactivity SupplierMouse
- Reactivity Supplier NoteAntibody developed using protein corresponding to amino acids 2 to 447 of the Lfc protein fused to GST.
- UNSPSC12352203
References
- 1. Glaven, J.A., et al. The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells. J. Biol. Chem. 1999, 274, 2279-2285 2. Glaven, J.A., et al. Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein. J. Biol. Chem. 1996, 271, 27374-27381 3. Whitehead, I., et al. Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C. J. Biol. Chem. 1995, 270, 18388-18395