GEF-H1 antibody
GTX125893
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetARHGEF2
Overview
- SupplierGeneTex
- Product NameGEF-H1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.71 mg/ml
- ConjugateUnconjugated
- Gene ID9181
- Target nameARHGEF2
- Target descriptionRho/Rac guanine nucleotide exchange factor 2
- Target synonymsGEF, GEF-H1, GEFH1, LFP40, Lfc, NEDMHM, P40, rho guanine nucleotide exchange factor 2, Rho/Rac guanine nucleotide exchange factor (GEF) 2, guanine nucleotide exchange factor H1, microtubule-regulated Rho-GEF, proliferating cell nucleolar antigen p40
- HostRabbit
- IsotypeIgG
- Protein IDQ92974
- Protein NameRho guanine nucleotide exchange factor 2
- Scientific DescriptionRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ueda Y, Higasa K, Kamioka Y, et al. Rap1 organizes lymphocyte front-back polarity via RhoA signaling and talin1. iScience. 2023,26(8):107292. doi: 10.1016/j.isci.2023.107292Read this paper
- Hetmanski JHR, de Belly H, Busnelli I, et al. Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration. Dev Cell. 2019,51(4):460-475.e10. doi: 10.1016/j.devcel.2019.09.006Read this paper
- Liang Z, Zhan Y, Shen Y, et al. The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines. Nat Commun. 2016,7:13282. doi: 10.1038/ncomms13282Read this paper
- Wang HL, Yang CH, Lee HH, et al. Dexamethasone-induced cellular tension requires a SGK1-stimulated Sec5-GEF-H1 interaction. J Cell Sci. 2015,128(20):3757-68. doi: 10.1242/jcs.169961Read this paper
- Huang IH, Hsiao CT, Wu JC, et al. GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment. J Cell Sci. 2014,127(Pt 19):4186-200. doi: 10.1242/jcs.150227Read this paper
Datasheet
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