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GEF-H1 antibody

GTX125893
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetARHGEF2
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Overview

  • Supplier
    GeneTex
  • Product Name
    GEF-H1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.71 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9181
  • Target name
    ARHGEF2
  • Target description
    Rho/Rac guanine nucleotide exchange factor 2
  • Target synonyms
    GEF; GEFH1; GEF-H1; guanine nucleotide exchange factor H1; Lfc; LFP40; microtubule-regulated Rho-GEF; NEDMHM; P40; proliferating cell nucleolar antigen p40; rho guanine nucleotide exchange factor 2; Rho/Rac guanine nucleotide exchange factor (GEF) 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92974
  • Protein Name
    Rho guanine nucleotide exchange factor 2
  • Scientific Description
    Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Rap1 organizes lymphocyte front-back polarity via RhoA signaling and talin1.
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  • Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration. Hetmanski JHR et al., 2019 Nov 18, Dev Cell
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  • The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines. Liang Z et al., 2016 Oct 31, Nat Commun
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  • Dexamethasone-induced cellular tension requires a SGK1-stimulated Sec5-GEF-H1 interaction. Wang HL et al., 2015 Oct 15, J Cell Sci
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  • GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment. Huang IH et al., 2014 Oct 1, J Cell Sci
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