SHH, Human (HEK293, His)

MedChem Express

SHH, Human (HEK293, His)

10

Research Use Only

97.20

SHH

sonic hedgehog signaling molecule

HHG1, HLP3, HPE3, MCOPCB5, SMMCI, ShhNC, TPT, TPTPS, sonic hedgehog protein, SHH signaling molecule, shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, sonic hedgehog homolog

Sonic hedgehog protein

Sonic Hedgehog (SHH) Protein is a secretory glycoprotein of the Hedgehog family that can self-cleave to form N-SHH. SHH Protein activates Smo by binding to Frizzled and LRP6, inhibits GSK-3beta to stabilize beta-catenin, and activates FOXM1. SHH Protein also promotes NO release and shortens myocardial APD by phosphorylating eNOS through PI3K/Akt. SHH Protein can promote the maturation of sweat gland cells in three-dimensional culture and play a cardioprotective role in the pig ischemia-reperfusion model[1][2]. SHH Protein, Human (HEK293, His) is a recombinant human SHH protein expressed in HEK293 cells with C-terminal His-tag.

-20°C

41116100

Human