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Shield-1

HY-112210
MedChem Express
CAS Number914805-33-7
Product group Chemicals
Estimated Purity99.73
Molecular Weight748.90
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Shield-1 [914805-33-7]
  • Delivery Days Customer
    10
  • CAS Number
    914805-33-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.73
  • Molecular Formula
    C42H56N2O10
  • Molecular Weight
    748.90
  • Scientific Description
    Shield-1 (Shld1) is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 ( FKBP ), and reverses the instability by binding to mutated FKBP (mtFKBP) , allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize proteins tagged with a mutated FKBP12-derived destabilization domain (DD) [1] [2] [3] .
  • SMILES
    O=C([C@H]1N(C([C@H](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[C@@H](C3=CC=CC(OCCN4CCOCC4)=C3)CCC5=CC=C(OC)C(OC)=C5
  • Storage Instruction
    -80°C
  • UNSPSC
    12352200