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Shield-1 [914805-33-7]

Shield-1 [914805-33-7]

T13884
TargetMol Chemicals
CAS Number914805-33-7
Product group Chemicals
Estimated Purity99.22%
Molecular Weight748.9
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Shield-1 [914805-33-7]
  • Delivery Days Customer
    9
  • CAS Number
    914805-33-7
  • Certification
    Research Use Only
  • Chemical Name
    Shield-1
  • Estimated Purity
    99.22%
  • Molecular Formula
    C42H56N2O10
  • Molecular Weight
    748.9
  • Scientific Description
    Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP) and reverses instability by binding to mutant FKBP (mtFKBP), allowing conditional expression of mtFKBP fusion proteins.
  • Shelf life instruction
    3 years
  • SMILES
    CC[C@H](C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1cccc(OCCN2CCOCC2)c1)c1cc(OC)c(OC)c(OC)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Banaszynski LA, Chen LC, Maynard-Smith LA, et al. A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules. Cell. 2006,126(5):995-1004.
    Read this paper