SHIN1

MedChem Express

SHIN1 [2146095-85-2]

10

2146095-85-2

Research Use Only

99.11

C24H24N4O2

400.47

SHIN1 (RZ-2994) is a human serine hydroxymethyltransferse 1 and 2 ( SHMT1/2 ) inhibitor with IC 50 s of 5 and 13 nM, respectively, in an in vitro assay.

OCC1=CC(C2=CC=CC=C2)=CC(C3(C(C(C)=NN4)=C4OC(N)=C3C#N)C(C)C)=C1

-20°C,2°C to 8°C

12352200