Shizukaol B [142279-40-1]

MedChem Express

Shizukaol B [142279-40-1]

10

142279-40-1

Research Use Only

96.0

C40H44O13

732.77

Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-alpha, and IL-1beta expression[1].

COC(/C(C)=C1[C@]2([H])[C@@]34[C@](CC5=C2[C@]([C@@]6([H])[C@]5([H])C6)([C@H](C/1=O)O)C)([H])[C@]7([C@@]8([H])[C@]([C@@]9([C@]7([H])CC3=C(COC(CCC(OC/C=C(C(OC9)=O)/C)=O)=O)C(O4)=O)O)([H])C8)C)=O

-20°C

12352200