SHP1 antibody [PTY11]

GeneTex

SHP1 antibody [PTY11]

9

This antibody recognizes single 67 kDa PTP1-C in human cells that express the enzyme.

ELISA: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 67 kDa. Optimal dilutions/concentrations should be determined by the end user.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

PTY11

1 mg/ml

Unconjugated

Liquid

PTPN6

protein tyrosine phosphatase non-receptor type 6

HCP; HCPH; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; protein-tyrosine phosphatase 1C; protein-tyrosine phosphatase SHP-1; PTP-1C; SHP1; SHP-1; SHP-1L; SH-PTP1; tyrosine-protein phosphatase non-receptor type 6

Mouse

IgG1

Tyrosine-protein phosphatase non-receptor type 6

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203