Various whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with SHP2 antibody [SD20-75] (GTX01144) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Various whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with SHP2 antibody [SD20-75] (GTX01144) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
SHP2 antibody [SD20-75] - Recombinant antibody Validated
GTX01144
Overview
- SupplierGeneTex
- Product NameSHP2 antibody [SD20-75] - Recombinant antibody Validated
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSD20-75
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5781
- Target namePTPN11
- Target descriptionprotein tyrosine phosphatase non-receptor type 11
- Target synonymsBPTP3; CFC; JMML; METCDS; NS1; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; PTP-1D; PTP2C; SH2 domain-containing protein tyrosine phosphatase 2; SHP2; SH-PTP2; SH-PTP3; tyrosine-protein phosphatase non-receptor type 11
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203