SHP2 (phospho Tyr580) antibody

GeneTex

SHP2 (phospho Tyr580) antibody

9

IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

PTPN11

protein tyrosine phosphatase non-receptor type 11

BPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2, tyrosine-protein phosphatase non-receptor type 11, SH2 domain-containing protein tyrosine phosphatase 2, protein-tyrosine phosphatase 1D, protein-tyrosine phosphatase 2C

Rabbit

IgG

Tyrosine-protein phosphatase non-receptor type 11

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203