Simufilam (hydrochloride) [2480226-07-9]

MedChem Express

Simufilam (hydrochloride) [2480226-07-9]

10

2480226-07-9

Research Use Only

99.85

C15H22ClN3O

295.81

Simufilam hydrochloride (PTI-125 hydrochloride) is an orally active FLNA modulator. Simufilam hydrochloride restores NMDAR signaling and Arc expression. Simufilam hydrochloride inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Abeta42-induced neuroinflammation and tau protein hyperphosphorylation. Simufilam hydrochloride can be used for research of Alzheimers disease[1][2][3].

O=C1N(CC2=CC=CC=C2)C3(CCN(C)CC3)NC1.[H]Cl

2°C to 8°C

12352200