Simufilam hydrochloride [2480226-07-9]

TargetMol Chemicals

Simufilam hydrochloride [2480226-07-9]

14

2480226-07-9

Chemical

Research Use Only

Simufilam hydrochloride

C15H22ClN3O

295.81

Simufilam (PTI-125) (hydrochloride) is an orally active filamin A (FLNA) activator with low toxicity that can be used in the Alzheimers disease research. Simufilam (hydrochloride) preferentially binds to altered FLNA and restores its native conformation, restores receptor and synaptic activities, and reduces its a7nAChR/TLR4 associations and downstream pathologies [1].

3 years

Cl.CN1CCC2(CC1)NCC(=O)N2Cc1ccccc1

-20°C

12352200