IHC image of CSB-PA021328LA01HU diluted at 1:400 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system.
IHC image of CSB-PA021328LA01HU diluted at 1:400 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system.
SIN3B Antibody
CSB-PA021328LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSIN3B
Overview
- SupplierCusabio
- Product NameSIN3B Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23309
- Target nameSIN3B
- Target descriptionSIN3 transcription regulator family member B
- Target synonymshistone deacetylase complex subunit Sin3b; paired amphipathic helix protein Sin3b; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator homolog B; transcriptional corepressor Sin3b
- HostRabbit
- IsotypeIgG
- Protein IDO75182
- Protein NamePaired amphipathic helix protein Sin3b
- Scientific DescriptionActs as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203