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SIRT7 inhibitor 97491

HY-135899
MedChem Express
CAS Number1807758-81-1
Product group Chemicals
Estimated Purity98.03
Molecular Weight285.73
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SIRT7 inhibitor 97491 [1807758-81-1]
  • Delivery Days Customer
    9
  • CAS Number
    1807758-81-1
  • Certification
    Research Use Only
  • Estimated Purity
    98.03
  • Molecular Formula
    C15H12ClN3O
  • Molecular Weight
    285.73
  • Scientific Description
    SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC 50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway. [1] .
  • SMILES
    NC1=CC(NC2=NC=C(C3=CC=C(Cl)C=C3)O2)=CC=C1
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200