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SIRT7 inhibitor 97491

M28898
AbMole BioScience
CAS Number1807758-81-1
Product group Chemicals
Molecular Weight285.73
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    SIRT7 inhibitor 97491
  • Delivery Days Customer
    9
  • CAS Number
    1807758-81-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C15H12ClN3O
  • Molecular Weight
    285.73
  • Scientific Description
    SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.
  • SMILES
    NC1=CC=CC(=C1)NC2=NC=C(O2)C3=CC=C(Cl)C=C3
  • Storage Instruction
    4°C, protect from light
  • UNSPSC
    12352200

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