Sivelestat (sodium tetrahydrate)

MedChem Express

Sivelestat (sodium tetrahydrate) [201677-61-4]

10

201677-61-4

Research Use Only

99.90

C20H29N2NaO11S

528.51

Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase , with an IC 50 of 44 nM and a K i of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 [1] [2] [3] [4] .

CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O[Na])=O)=O)=O)C=C1)=O.O.O.O.O

2°C to 8°C

12352200