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Sivelestat sodium tetrahydrate

M5966
AbMole BioScience
CAS Number201677-61-4
DownloadDatasheet
Product group Chemicals
Estimated Purity0.9962
Molecular Weight528.51
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Sivelestat sodium tetrahydrate
  • Delivery Days Customer
    9
  • CAS Number
    201677-61-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9962
  • Molecular Formula
    C20H21N2O7S.4H2O.Na
  • Molecular Weight
    528.51
  • Scientific Description
    Sivelestat sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
  • SMILES
    O.O.O.O.[Na+].CC(C)(C)C(=O)OC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=CC=C2C(=O)NCC([O-])=O
  • UNSPSC
    12352200