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SLUG antibody

Name: SLUG antibody
SKU: GTX121924_G10
Availability: BackOrder

GTX121924

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetSNAI2

Overview

Supplier
GeneTex
Product Name
SLUG antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID6591
Target name
SNAI2
Target description
snail family transcriptional repressor 2
Target synonyms
SLUG, SLUGH, SLUGH1, SNAIL2, WS2D, zinc finger protein SNAI2, neural crest transcription factor SLUG, protein snail homolog 2, slug (chicken homolog), zinc finger protein, snail family zinc finger 2, snail homolog 2
Host
Rabbit
Isotype
IgG
Protein IDO43623
Protein Name
Zinc finger protein SNAI2
Scientific Description
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Chang YX, Lin YF, Chen CL, et al. Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-Catenin and XIAP-Survivin Pathways. Cancers (Basel). 2020,12(12). doi: 10.3390/cancers12123865
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Soyama H, Miyamoto M, Ishibashi H, et al. Placenta previa may acquire invasive nature by factors associated with epithelial-mesenchymal transition and matrix metalloproteinases. J Obstet Gynaecol Res. 2020,46(12):2526-2533. doi: 10.1111/jog.14485
Read this paper
Liu YH, Weng YP, Lin HY, et al. Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Sci Rep. 2017,7:41437. doi: 10.1038/srep41437
Read this paper
Cheng M, Ho S, Yoo JH, et al. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clin Exp Gastroenterol. 2015,8:13-29. doi: 10.2147/CEG.S70906
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Kuo TC, Tan CT, Chang YW, et al. Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility. J Clin Invest. 2013,123(3):1082-95. doi: 10.1172/JCI64044
Read this paper