SMARCC1 Antibody

Cusabio

SMARCC1 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

SMARCC1

SWI/SNF related BAF chromatin remodeling complex subunit C1

BAF155, CRACC1, HYC5, Rsc8, SRG3, SWI3, SWI/SNF complex subunit SMARCC1, BRG1-associated factor 155, SWI/SNF complex 155 kDa subunit, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1, chromatin remodeling complex BAF155 subunit, mammalian chromatin remodeling complex BRG1-associated factor 155

Rabbit

IgG

SWI/SNF complex subunit SMARCC1

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Human

-20°C or -80°C

41116161