SMRT antibody [1542]
GTX70248
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetNCOR2
Overview
- SupplierGeneTex
- Product NameSMRT antibody [1542]
- Delivery Days Customer9
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1542
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9612
- Target nameNCOR2
- Target descriptionnuclear receptor corepressor 2
- Target synonymsCTG repeat protein 26; CTG26; N-CoR2; nuclear receptor corepressor 2; silencing mediator for retinoid and thyroid hormone receptors; SMAP270; SMRT; SMRTE; SMRTE-tau; T3 receptor-associating factor; thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC1; TRAC-1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Repressors of androgen and progesterone receptor action. Agoulnik IU et al., 2003 Aug 15, J Biol ChemRead more
- Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT. Liao G et al., 2003 Feb 14, J Biol ChemRead more
- SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains. Wu X et al., 2001 Jun 29, J Biol ChemRead more