SN-38 [86639-52-3]

TargetMol Chemicals

SN-38 [86639-52-3]

10

86639-52-3

Chemical

Research Use Only

SN-38

99.97%

C22H20N2O5

392.4

SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 microM). SN-38 has antitumor activity and induces autophagy.

3 years

C(C)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC(O)=CC5

-20°C

12352200