SNIPER(ABL)-058

MedChem Express

SNIPER(ABL)-058 [2222354-61-0]

10

2222354-61-0

Research Use Only

C62H75N11O9S

1150.39

SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 microM[1].

CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCOC4=CC(C(C5=CSC([C@H]6N(C([C@H](C7CCCCC7)NC([C@H](C)NC)=O)=O)CCC6)=N5)=O)=CC=C4)=O)CC3)C=C2)=O)C=C1NC8=NC=CC(C9=CC=CN=C9)=N8

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