SNIPER(ABL)-058

Biorbyt

SNIPER(ABL)-058 [2222354-61-0]

10

2222354-61-0

Research Use Only

98.00%

C62H75N11O9S

1150.39

SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL protein levels, achieving a half-maximal degradation concentration (DC50) of 10 microM[1].

C([C@@H](NC([C@@H](NC)C)=O)C1CCCCC1)(=O)N2[C@@](CCC2)(C3=NC(C(=O)C4=CC(OCCOCCOCCOCC(=O)N5CCN(CC6=CC=C(C(NC7=CC(NC=8N=C(C=CN8)C=9C=CC=NC9)=C(C)C=C7)=O)C=C6)CC5)=CC=C4)=CS3)[H]

-20°C

12352200